Convergent MurJ flippase inhibition by phage lysis proteins

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Before agar, microbiologists had experimented with other foodstuffs as microbial media. They turned to substances rich in the starches, proteins, sugars, fats, and minerals that organisms need for growth, testing with broths, bread, potatoes, polenta, egg whites, coagulated blood serums, and gelatine. However, none worked particularly well: all were easily broken down by heat and microbial enzymes, and their surface, once colonized, became mushy and unsuitable for isolating microbes.

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That is not only a sadness and a loss, but becoming an aged society is a cultural and economic threat. Older people, by and large, are not the innovators or new thinkers. An ageing society risks declining in optimism, creativity and, above all, risk-taking: a top-heavy preponderance of older people makes for a conservative and fearful electorate. We are there already – and it’s getting worse.

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